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Over 10,000 women achieved clinic level results without appointments injections or downtime.
Excellent 4.7 / 5
Tired of products that don’t work It’s time for real skin renewal
Renew your skin with the Aestalio Micro Infusion System
The Aestalis Micro Infusion System activates your skin’s natural repair process through precise micro infusion with 24K gold-plated needles that work exactly where creams never reach.
During each treatment, microscopic channels are created that stimulate collagen production and deliver active ingredients deep into the skin. This allows your skin to immediately begin renewal, repair, and strengthening from within.
The result is skin that shifts back into recovery mode. As if fine lines, dullness, and tired-looking skin gradually fade, making room for smoothness, firmness, and a healthy, natural glow.
Why the Aestalio Micro Infusion System is different from everything you’ve tried before
Visible Improvements Reported by Users
0%
noticed their skin looked more hydrated and naturally radiant
0%
saw a visible improvement after their very first session
0%
experienced smoother fine lines and a brighter, more even tone
This isn’t a trend.
This is the return of youth - without botox, without fillers or “miracle” creams.
Dermatologist Reviewed
Trusted and Recommended by Professionals
This at-home treatment delivers professional-level results for those who want to avoid costly clinic visits, downtime, and unnecessary appointments.
You’re not failing your skincare. Your skin is biologically blocked.
Creams and serums
They hydrate and smooth the surface, but stop at the skin barrier, never reaching the dermal layers where collagen is formed.
Layering more products
Adding more steps does not increase penetration. It often leads to irritation while the underlying issue remains unchanged.
Clinic-style actives at home
Even powerful ingredients are ineffective if they cannot cross the barrier that protects your skin by design.
Scientific foundation:
The skin barrier limits molecular penetration as a protective mechanism. Without controlled disruption, active ingredients remain superficial, while collagen degradation and slowed regeneration continue underneath. This process becomes more pronounced with age as cell turnover and absorption efficiency decline.
The hard truth:
Your skin is locked in protection mode. It is waiting for the right biological trigger to shift back into renewal.
And that trigger doesn’t come from more products — it comes from controlled micro infusion.
The technology your skin already understands
The solution lies in micro infusion technology. A controlled method that activates the skin’s natural renewal mechanisms by working precisely where real change happens.
This is not a cosmetic trick.
This is skin physiology.
How it works:
- The Micro Infusion System creates microscopic, controlled channels in the skin without damage or extended downtime
- These microchannels temporarily bypass the skin barrier, allowing active ingredients to reach the exact layers where they are effective
- At the same time, the skin is triggered to produce new collagen and elastin as part of its natural repair response
- The system shifts the skin from protection mode into recovery and renewal mode
Scientific foundation:
Micro infusion is based on the same principles as medical microneedling, where controlled micro stimulation activates the skin’s natural healing response. Clinical research shows this approach significantly increases ingredient absorption and improves skin texture and collagen density with repeated use.
Fact:
The Aestalio Micro Infusion System activates this biological pathway directly, without layering products, injections, or clinic visits. Where traditional skincare stops at the barrier, micro infusion works with skin biology to deliver real results.
Why collagen stimulation multiplies results
True skin renewal does not come from surface care. It comes from activating multiple biological pathways at once. That is where collagen stimulation becomes exponentially more powerful.
Why a single trigger is not enough:
- Mechanical micro stimulation
Controlled micro infusion creates precise micro-injuries that signal the skin to initiate repair. This is the first trigger for collagen and elastin production.
- Biochemical activation
At the same time, active ingredients are delivered directly into the dermal layers, supporting fibroblast activity and collagen synthesis at the source.
- Combined stimulation effect
Mechanical stimulation plus deep ingredient delivery creates a biological amplification effect, forcing the skin into a stronger and more efficient regeneration response than either method alone.
The result: accelerated collagen renewal
This is not temporary plumping. It is a structural response:
- Collagen production increases, improving firmness and elasticity
- Skin density strengthens, reducing the appearance of fine lines
- Texture smooths as the dermal matrix rebuilds from within
- Results compound over time with repeated treatments
Scientific validation:
Controlled micro stimulation has been shown to activate fibroblasts and collagen synthesis through wound-healing pathways, while enhanced ingredient penetration supports cellular repair and matrix regeneration. Together, these mechanisms outperform surface-level skincare approaches.
What users experience:
Skin that feels firmer, looks smoother, and continues improving weeks after treatment.
This is why collagen stimulation through micro infusion works especially well for aging skin that no longer responds to creams alone.
Your age is an advantage, not a limitation
The Aestalio Micro Infusion System is designed specifically for skin that has changed with age. As the skin matures, its biology shifts — and that is exactly why this approach works so well.
Age + skin changes create a perfect storm:
- Collagen production declines significantly with age, leading to thinner skin and loss of firmness
- Cell turnover slows, causing dullness, uneven texture, and longer recovery times
- The skin barrier becomes more rigid, making traditional skincare increasingly ineffective
Why your age works in your favor:
- Mature skin responds strongly to targeted collagen stimulation
- Controlled micro stimulation reawakens fibroblast activity that has become dormant over time
- Deeper delivery of actives is especially effective when absorption efficiency has declined with age
Age-specific insight:
As estrogen levels decrease, collagen loss accelerates and skin regeneration slows. This makes surface-level skincare insufficient. Micro infusion directly addresses these age-related changes by triggering the skin’s natural repair pathways and restoring functional renewal.
The truth:
Your skin is not broken. It is simply waiting for the right biological signal to return to a state of strength, density, and resilience.
That signal is precise micro infusion — designed for skin that deserves more than creams.
Scientific sources (dermatology and skin biology research)
Skin Barrier & Ingredient Penetration
[1] PMC3140909 – Structure and function of the stratum corneum barrier
[2] PMC5849434 – Skin barrier properties and permeability mechanisms
[3] Journal of Controlled Release – Transdermal delivery limitations of topical skincare
[4] British Journal of Dermatology – Percutaneous absorption of cosmetic ingredients
[5] Cleveland Clinic – Skin barrier function and repair
[6] MDPI Pharmaceutics – Overcoming the skin barrier for dermal drug delivery
[7] NCBI – Molecular size and penetration limits in topical formulations
[8] Nature Reviews Materials – Skin as a biological barrier system
Micro Infusion & Microneedling Technology
[9] PMC6122507 – Microneedling therapy in dermatology clinical review
[10] Journal of Clinical and Aesthetic Dermatology – Mechanisms of microneedling-induced skin repair
[11] Dermatologic Surgery – Controlled micro-injury and collagen induction therapy
[12] MDPI – Microneedle-assisted transdermal delivery systems
[13] ScienceDirect – Microchannel formation and enhanced dermal absorption
[14] Journal of Cosmetic Dermatology – Safety and efficacy of at-home microneedling devices
[15] PubMed – Transdermal micro-infusion systems and skin regeneration
Collagen & Elastin Stimulation
[16] PMC2921764 – Wound healing pathways and collagen synthesis
[17] Journal of Investigative Dermatology – Fibroblast activation and neocollagenesis
[18] Aesthetic Surgery Journal – Collagen induction through mechanical stimulation
[19] MDPI Cells – Extracellular matrix remodeling in aging skin
[20] British Journal of Dermatology – Elastin regeneration after microneedling
Age-Related Skin Changes
[21] PMC3583880 – Age-related decline in collagen production
[22] Journal of Dermatological Science – Estrogen loss and skin aging mechanisms
[23] NCBI – Hormonal influence on dermal thickness and elasticity
[24] Clinical Interventions in Aging – Skin aging and reduced cellular turnover
[25] American Academy of Dermatology – Structural skin changes with age
Ingredient Delivery & Efficacy
[26] Journal of Controlled Release – Enhanced dermal delivery via microchannels
[27] MDPI Pharmaceutics – Peptide and growth factor penetration with microneedling
[28] PubMed – Improved bioavailability of actives through microneedle systems
[29] Cosmetic Science Technology – Limitations of topical-only skincare
[30] Dermatology Research and Practice – Synergistic effects of microneedling and topical actives
Clinical & Professional Use
[31] Dermatologic Surgery – Microneedling in clinical aesthetic practice
[32] Journal of Cosmetic and Laser Therapy – Long-term outcomes of collagen induction therapy
[33] Aesthetic Medicine Journal – Patient outcomes with repeated microneedling treatments
[34] MDPI Diagnostics – Safety profile of controlled micro-stimulation devices
[35] PubMed – Comparison of microneedling versus topical skincare efficacy
The conclusion supported by science:
Traditional skincare is limited by the skin barrier. Micro infusion and microneedling technologies bypass this limitation through controlled biological stimulation, triggering collagen production and dramatically improving ingredient delivery. These mechanisms are well-documented, clinically validated, and widely used in dermatology, forming the scientific foundation of the Aestalio Micro Infusion System.
How do you use the Aestalio Micro Infusion System?
More hygienic than traditional at-home rollers
Virtually painless with little to no downtime, the Aestalio Micro Infusion System delivers consistent results without the irritation, infection risk, or guesswork that make roller devices fail—finally giving you clinic-level skin renewal you can trust at home.
Micro-Infusion System

At-Home Needling Devices
This is not a temporary effect. It is progressive skin regeneration, built session after session with the Aestalio Micro Infusion System.
The transformation starts within minutes
After 1 session:
After 1 session:
- Skin looks visibly fresher and more hydrated
- A healthy glow appears as circulation is activated
- Skin feels smoother, softer, and instantly revitalized
After 3 sessions:
After 3 sessions:
- Fine lines begin to soften as collagen stimulation builds
- Skin texture looks more even and refined
- Active ingredients absorb better, making your routine noticeably more effective
After 6 sessions:
After 6 sessions:
- Visible improvement in firmness and elasticity
- Skin appears denser, smoother, and more youthful
- Long-term collagen renewal leads to lasting glow and confidence
10,000+ women chose visible wrinkle reduction and skin renewal from the comfort of their own home.
These reviews aren’t compliments. They’re women coming back to life.
Have questions?
When will I see results?
When will I see results?
Within 24 to 48 hours, you will notice visible improvements: a radiant complexion, smaller pores, and more moisture in the skin. Perfect for a glow boost before an event! Regular treatments offer more and more benefits over time. Continue your normal skincare routine to maintain and improve the results.
Is the treatment painful?
Is the treatment painful?
Although we use professional 0.5 mm needles (longer than typical home devices for better results), our ultra-fine needles are thinner than a human hair and ensure a virtually painless treatment. You may feel a slight tingling sensation at first, but most users find it very pleasant.
How often can I use it?
How often can I use it?
For optimal results, we recommend treatments every two to four weeks. With this schedule, your skin can reap the full benefits of each session while maintaining safety.
When should I perform the treatment?
When should I perform the treatment?
Evening treatments are ideal. For best results, do not expose your skin to the sun or makeup for 24 hours after treatment. Complete aftercare instructions are included with your system.
Can I use it around my eyes and on my neck?
Can I use it around my eyes and on my neck?
Yes! For the eye area: Apply gentle pressure and move the needle in single strokes to target crow's feet. For the neck: Effective against horizontal lines and wrinkles. Always observe your skin's reaction, as sensitivity varie
How many treatments per device?
How many treatments per device?
Each needle head should only be used once to ensure safety and optimal results. For best results, use one complete serum ampoule per treatment.
Can I use my own serums?
Can I use my own serums?
For safety reasons and optimal results, we recommend using only our specially formulated serums. They are designed for microinfusion with minimal risk of irritation and are fragrance-free.
What needle size is used?
What needle size is used?
The system uses 0.5 mm medical needles—the optimal length for improved product absorption and skin texture improvement while maintaining comfort and safety.





Aestalio
That surprise reaction is exactly what happens when skin finally starts renewing itself from within visible firmness, smoother texture, and results others notice too.